Ongoing Study:
Phase 1b/2 Study of Annamycin in STS Lung Mets in the United States
Multi-Center, Open-Label, Single-Arm Study of Liposomal Annamycin for the Treatment of Subjects with Soft-Tissue Sarcomas (STS) With Pulmonary Metastases
Promising Early Clinical Activity in Phase 1b/2
Study Highlights:
Enrolling: ~18 Subjects in 1b portion
Treatment period: Single dose every 21 days
Does Escalation: From 210 mg to a max of 450 mg (currently enrolling 390 mg)
Primary Endpoint: Establish MTD/RP2D and safety
Planned Phase 2 expansion (25 patients) will evaluate efficacy
For complete study details, please view the study listing on clinicaltrials.gov: ClinicalTrials.gov Identifier: NCT04887298