Ongoing Study:

Phase 1b/2 Study of Annamycin in STS Lung Mets in the United States

Multi-Center, Open-Label, Single-Arm Study of Liposomal Annamycin for the Treatment of Subjects with Soft-Tissue Sarcomas (STS) With Pulmonary Metastases

Preliminary Phase 1b Data Demonstrated No Cardiotoxicity

and Demonstrated Clinical Activity1

Study Highlights:

Enrolling: ~25 Subjects in Phase 2 portion

Treatment Period: Single dose every 21 days

RP2D: 360mg/m2 (protocol provides for a reduction to 330 mg/m2 after the first 3 patients treated if warranted based on tolerability)

Phase 1b Concluded: RP2D determined to be 360mg/m2

Phase 2 Recruitment Open: Expansion at 360 mg/m2 with option to decrease to 330 mg/m2

For complete study details, please view the study listing on Identifier: NCT04887298

1: Data are preliminary. Defined as stable disease or better. As of August 12, 2022, preliminary data demonstrated 12 of 14 patients measured had SD after two cycles of Annamycin.

Our Pipeline


Sign Up For Alerts